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Volume 16, Issue 1 (2024)
Iran J War Public Health 2024, 16(1): 75-79 |
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Received: 2023/12/27 | Accepted: 2024/04/4 | Published: 2024/04/10
Received: 2023/12/27 | Accepted: 2024/04/4 | Published: 2024/04/10
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Sherhan A. A Comparison of the Effect of Multiple Inhalers Compared to Single Inhalers Salbutamol and Steroid on Patients with Asthma. Iran J War Public Health 2024; 16 (1) :75-79
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Authors
A.A. Sherhan *
Department of Medicine, Basrah Medical College, University Basrah, Basrah, Iraq
Abstract (496 Views)
Aims: In chronic persistent bronchial asthma, the combination of inhaled long-acting B2-agonists with inhaled steroids has long been used to reduce hospital admissions and improve quality of life, as opposed to using either medication alone. This study aimed to determine whether this type of inhaler therapy for patients with chronic asthma reduces symptoms, decreases the need for hospital admissions, improves the quality of life, and whether a high-dose combination is superior to a low dose in managing patients.
Materials & Methods: In this prospective descriptive cross-sectional study, 207 patients with chronic persistent bronchial asthma, using various inhalers, were randomly enrolled, of whom 120 cases (58.0%) were female and 87 cases (42.0%) were male, with ages ranging from 16 to 75 and a mean age of 45.59±14.67 years. The study assessed the type and dose of inhalers used, control over asthma symptoms, hospital admission rates, inhaler adherence, confidence in treatment, and pulmonary function test parameters (FEV1, FVC, and PEFR) while patients used their prescribed inhalers.
Findings: We found a statistically significant difference in FEV1/FVC between patients using single inhalers and those using combined inhaler therapy for chronic persistent asthma (p=0.005). However, there was no significant difference between the types of combined inhaler therapies (p=0.12). Age had no statistically significant effect in either comparison (p=0.85, 0.47, respectively).
Conclusions: Combined inhaler therapy for patients with persistent asthma is preferred by patients and shows superior efficacy compared to using either medication alone. Age does not significantly influence treatment response or patient preference.
Materials & Methods: In this prospective descriptive cross-sectional study, 207 patients with chronic persistent bronchial asthma, using various inhalers, were randomly enrolled, of whom 120 cases (58.0%) were female and 87 cases (42.0%) were male, with ages ranging from 16 to 75 and a mean age of 45.59±14.67 years. The study assessed the type and dose of inhalers used, control over asthma symptoms, hospital admission rates, inhaler adherence, confidence in treatment, and pulmonary function test parameters (FEV1, FVC, and PEFR) while patients used their prescribed inhalers.
Findings: We found a statistically significant difference in FEV1/FVC between patients using single inhalers and those using combined inhaler therapy for chronic persistent asthma (p=0.005). However, there was no significant difference between the types of combined inhaler therapies (p=0.12). Age had no statistically significant effect in either comparison (p=0.85, 0.47, respectively).
Conclusions: Combined inhaler therapy for patients with persistent asthma is preferred by patients and shows superior efficacy compared to using either medication alone. Age does not significantly influence treatment response or patient preference.
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