JMERC
Owner
Janbazan Medical and Engineering Research Center (JMERC) is the owner of IJWPH.
0.4
Cite Score
SJR: 0.114 / SNIP: 0.090
Volume 16, Issue 1 (2024)
Iran J War Public Health 2024, 16(1): 43-48 |
Back to browse issues page
Article Type:
Subject:
History
Received: 2023/09/27 | Accepted: 2024/01/18 | Published: 2024/02/10
Received: 2023/09/27 | Accepted: 2024/01/18 | Published: 2024/02/10
How to cite this article
Baqir Q, Baqer G, Baqer F, Abbas B. Relationship of ABO and Lewis Blood Groups in Patients with Urinary Tract Infection. Iran J War Public Health 2024; 16 (1) :43-48
URL: http://ijwph.ir/article-1-1401-en.html
URL: http://ijwph.ir/article-1-1401-en.html
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Rights and permissions
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
1- Department of Surgery, College of Medicine, University of Basrah, Basrah, Iraq
2- Department of Human Anatomy, College of Medicine, University of Basrah, Basrah, Iraq
3- Department of Surgery, AL-Sader Teaching Hospital, Basrah, Iraq
4- Department of Microbiology, College of Veterinary Medicine, University of Basrah, Basrah, Iraq
2- Department of Human Anatomy, College of Medicine, University of Basrah, Basrah, Iraq
3- Department of Surgery, AL-Sader Teaching Hospital, Basrah, Iraq
4- Department of Microbiology, College of Veterinary Medicine, University of Basrah, Basrah, Iraq
Abstract (1149 Views)
Aims: Urinary tract infection is the most common adult bacterial infection worldwide. Antigens of ABO and Lewis blood groups may influence bacterial adherence and lead to an increase in the frequency of urinary tract infections in adults. This study aimed to evaluate the relationship of ABO and Lewis blood groups with urinary tract infections.
Materials & Methods: In this experimental study, a blood sample of 80 urinary tract infection patients from AL-Sader Teaching Hospital, Iraq, and 50 healthy persons was used for the determination of ABO and Lewis blood groups by agglutination assay. Urine samples of urinary tract infection patients were cultured and identified based on culture characteristics, gram staining, and biochemical tests.
Findings: Urinary tract infection was significantly higher in patients with the O blood group (42.5%) and the Lewis (a-b-) phenotype (38.8%) than in patients with other blood groups and the control group. Escherichia coli was the most common bacterial isolate observed in urinary tract infection patients. Also, E. coli was significantly higher in the UTI patients with the O blood group and the Lewis (a-b-) phenotype.
Conclusion: People of the O blood group and the Lewis (a-b-) phenotype are more susceptible to urinary tract infections. Escherichia coli is the main cause of urinary tract infections.
Materials & Methods: In this experimental study, a blood sample of 80 urinary tract infection patients from AL-Sader Teaching Hospital, Iraq, and 50 healthy persons was used for the determination of ABO and Lewis blood groups by agglutination assay. Urine samples of urinary tract infection patients were cultured and identified based on culture characteristics, gram staining, and biochemical tests.
Findings: Urinary tract infection was significantly higher in patients with the O blood group (42.5%) and the Lewis (a-b-) phenotype (38.8%) than in patients with other blood groups and the control group. Escherichia coli was the most common bacterial isolate observed in urinary tract infection patients. Also, E. coli was significantly higher in the UTI patients with the O blood group and the Lewis (a-b-) phenotype.
Conclusion: People of the O blood group and the Lewis (a-b-) phenotype are more susceptible to urinary tract infections. Escherichia coli is the main cause of urinary tract infections.
Keywords:
References
1. Foxman B. The Epidemiology of Urinary Tract Infection. Nat Rev Urol. 2010;7(12):653-60. [Link] [DOI:10.1038/nrurol.2010.190]
2. Hrbacek J, Cermak P, Zachoval R. Current antibiotic resistance trends of uropathogens in Central Europe: Survey from a Tertiary hospital urology department 2011-2019. Antibiotics. 2022;9(9):630. [Link] [DOI:10.3390/antibiotics9090630]
3. Flores-Mireles AL, Walker JN, Caparon M, Hultgren SJ. Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nat Rev Microbiol. 2015;13(5):269-84. [Link] [DOI:10.1038/nrmicro3432]
4. Gilbert NM, O'brien VP, Hultgren S, Macones G, Lewis WG, Lewis AL. Urinary tract infection as a preventable cause of pregnancy complications: opportunities, challenges, and a global call to action. Glob Adv Health Med. 2013;2(5):59-69. [Link] [DOI:10.7453/gahmj.2013.061]
5. Kleina RD, Hultgrena SJ. Urinary tract infections: microbial pathogenesis, host-pathogen interactions and new treatment strategies. Nat Rev Microbiol. 2020; 18(4):211-26. [Link] [DOI:10.1038/s41579-020-0324-0]
6. Ronald A. The etiology of urinary tract infection: Traditional and emerging pathogens. Dis Mon. 2003;49(2):71-82. [Link] [DOI:10.1067/mda.2003.8]
7. Mancuso G, Midiri A, Gerace E, Marra M, Zummo S, Biondo C. Urinary tract infections: The current scenario and future prospects. Pathogens. 2023; 12(4):623. [Link] [DOI:10.3390/pathogens12040623]
8. Govindarajan DK, Kandaswamy K. Virulence factors of uropathogens and their role in host pathogen interactions. Cell Surface. 2022;8:100075. [Link] [DOI:10.1016/j.tcsw.2022.100075]
9. Shahab N, Ali C, Salih S. Isolation and Identification of bacteria causing urinary tract infections in children in Kirkuk city. Tikrit J Pure Sci. 2017;22(2):8-11. [Link] [DOI:10.25130/tjps.v22i2.622]
10. Dadi M, Senthilkumar B, Berhanu S. Prevalence, Antimicrobial susceptibility pattern of bacterial isolates, and associated factors of urinary tract infections among hiv-positive patients at Hiwot Fana Specialized University Hospital, Eastern Ethiopia. Can J Infect Dis Med Microbiol. 2019;2019:6780354. [Link] [DOI:10.1155/2019/6780354]
11. Ebede S, Nwafia I, Ohanu M, Ozumba U, Chukwuka C, Onyedum C. Blood groups distribution pattern among limited adult human population of district Gilgit, Gilgit-Baltistan, Pakistan. Int J Pure Appl Zool. 2018;6(2):18-24. [Link] [DOI:10.22259/2637-5575.0204001]
12. Watkins W. The ABO blood group system: Historical background. Transfus Med. 2001;11(4):243-65. [Link] [DOI:10.1046/j.1365-3148.2001.00321.x]
13. Franchini M, Liumbruno GM. ABO blood group: Old dogma, new perspectives. Clin Chem Lab Med. 2013;51(8):1545-53. [Link] [DOI:10.1515/cclm-2013-0168]
14. Ewald R, Sumner S. Blood type biochemistry and human disease. Wiley Interdiscip Rev Syst Biol Med. 2016;8(6):517-35. [Link] [DOI:10.1002/wsbm.1355]
15. Jiang XL, Ming T. Histo-blood group antigens as receptors for rotavirus, new understanding on rotavirus epidemiology and vaccine strategy. Emerging Microbes Infect. 2017;6(4):e22. [Link] [DOI:10.1038/emi.2017.30]
16. Marionneau S, Cailleau-Thomas A, Rocher J, Ryzhov I, Bovin N, Henry S. ABH and Lewis histo-blood group antigens: A model for the meaning of oligosaccharide diversity in the face of a changing world. Biochimie. 2001;83(7):565-73. [Link] [DOI:10.1016/S0300-9084(01)01321-9]
17. Prakobphol A, Leffler H, Fisher SJ. The high molecular-weight human mucin is the primary salivary carrier of ABH, Le(a), and Le(b) blood group antigens. Crit Rev Oral Biol Med. 1993;4(3-4):325-33. [Link] [DOI:10.1177/10454411930040031001]
18. Williams E, Korchagina E, Frame T, Ryzhov I, Bovin N, Henry S. Glycomapping the fine specificity of monoclonal and polyclonal Lewis antibodies with type-specific Lewis kodecytes and function-spacer-lipid constructs printed on paper. Transfusion (Paris). 2016;56(2):325-33. [Link] [DOI:10.1111/trf.13384]
19. Stowell CP, Stowell SR. Biologic roles of the ABH and Lewis histo-blood group antigens Part I: Infection and immunity. Vox Sanguinis. 2019;114()5:426-42. [Link] [DOI:10.1111/vox.12787]
20. Abegaz SB. Human ABO Blood Groups and Their Associations with Different Diseases. Biomed Res Int. 2021;2021:6629060. [Link] [DOI:10.1155/2021/6629060]
21. Heggelund JE, Varrot A, Imberty A, Krengel U. Histo-blood group antigens as mediators of infections. Curr Opin Struct Biol. 2017;44:190-200 [Link] [DOI:10.1016/j.sbi.2017.04.001]
22. Formosa-Dague C, Castelain M, Martin-Yken H, Dunker K, Dague E, Sletmoen M. The role of glycans in bacterial adhesion to mucosal surfaces: how can single molecule techniques advance our understanding?. Microorganisms. 2018;6(2):39. [Link] [DOI:10.3390/microorganisms6020039]
23. Sheinfeld J, Schaeffer AJ, Cordon-Cardo C, Rogatko A, Fair WR. Association of the Lewis blood group phenotype with recurrent urinary tract infections in women. N Engl J Med. 1989;320(12):773-77. [Link] [DOI:10.1056/NEJM198903233201205]
24. Ishitoya S, Yamamoto S, Mitsumori K, Ogawa O, Terai A. Non-secretor status is associated with female acute uncomplicated pyelonephritis. BJU Int. 2002;89:851-4. [Link] [DOI:10.1046/j.1464-410X.2002.02782.x]
25. Nelson CP, Hoberman A, Shaikh N, Keren R, Mathews R, Greenfield SP, et al. Antimicrobial resistance and urinary tract infection recurrence. Pediatrics. 2016;137(4):e20152490. [Link] [DOI:10.1542/peds.2015-2490]
26. Fenta A, Dagnew M, Eshetie S, Belachew T. Bacterial profile, antibiotic susceptibility pattern and associated risk factors of urinary tract infection among clinically suspected children attending at Felege-Hiwot comprehensive and specialized hospital, Northwest Ethiopia. A prospective study. BMC Infect Dis. 2020;20(1):673. [Link] [DOI:10.1186/s12879-020-05402-y]
27. Ghasemi N, Ayatollahi J, Mosadegh A, Mahdavi SM. Relationship between ABO blood group antigens and the type of pathogen in urinary tract infection in patients referred to university laboratories in Yazd. Sci J Iran Blood Transfus Organ. 2009;5(4):267-73. [Persian] [Link]
28. Magliano E, Grazioli V, Deflorio L, Leuci A, Mattina R, Romano P, et al. Gender and age-dependent etiology of community-acquired urinary tract infections. Scientific World J. 2012;2012:349597. [Link] [DOI:10.1100/2012/349597]
29. Pardeshi P. Prevalence of urinary tract infections and current scenario of antibiotic susceptibility pattern of bacteria causing UTI. Indian J Microbiol Res. 2018;5(3):334-8. [Link] [DOI:10.18231/2394-5478.2018.0070]
30. Deltourbe L, Mariano LL, Hreha TN, Hunstad DA, Ingersoll MA. The impact of biological sex on diseases of the urinary tract. Soci Mucosal Immunol. 2022;15:857-66. [Link] [DOI:10.1038/s41385-022-00549-0]
31. Hasan SA, Magtooph MG. Relationship of ABO blood group with Hemoglubin level, glucose level and urinary tract infection of pregnant women. J Thi Qar Sci. 2018;6(4):49-53. [Link] [DOI:10.32792/utq/utjsci/v6i4.66]
32. Safarkar R, Bonabi R, Massiha A, Dejagah S, Khani S, Abafat N, et al. Relationship between urinary tract bacterial infections and blood groups in patients referring to Alavi hospital in Ardabil, Iran in 1395. Sci J Nurs Midwifery Paramed Faculty. 2018;4(1):41-51. [Persian] [Link]
33. Mahmoudian AS, Jaras M, Jarhi A, Khajavi A, Mircheraghi SF. The prevalence of bacteruria and its relationship with ABO blood group in pregnant Women. Q Horizon Med Sci. 2021;27(3):302-17. [Link] [DOI:10.32598/hms.27.3.3213.1]
34. Galeev A, Suwandi A, Cepic A, Basu M, Baines JF, Grassl GA. The role of the blood group-related glycosyltransferases FUT2 and B4GALNT2 in susceptibility to infectious disease. Int J Med Microbiol. 2021;311(3):151487. [Link] [DOI:10.1016/j.ijmm.2021.151487]
35. Amjadi O. Blood Group: in Health and Diseases. Res Mol Med J. 2018;3(4):1-9. [Link]
36. D'Adamo PJ, Kelly GS. Related articles, links metabolic and immunologic consequences of ABH secretor and Lewis subtype status. Altern Med Rev. 2001;6(4):390-405. [Link]
37. Dahash SL, Al-Kuraishi AH, Al-Amir ZA. Presence of ABO antigens of blood types in saliva of women with urinary tract infection. Indian J Public Health Res Dev. 2018;9(11):468-74. [Link] [DOI:10.5958/0976-5506.2018.01500.0]
38. Sheinfeld J, Cordon-Cardo C, Fair WR, Wartinger DD, Rabinowitz R. Association of type 1 blood group antigens with urinary tract infections in children with genitourinary structural abnormalities. J Urol. 1990;144(2):469-73. [Link] [DOI:10.1016/S0022-5347(17)39492-2]
39. Navas EL, Venegas MF, Duncan JL, Anderson BE, Chmiel JS, Schaeffer AJ. Blood group antigen expression on vaginal and buccal epithelial cells and mucus in secretor and non-secretor women. J Urol. 1993;149(6):1492-98. [Link] [DOI:10.1016/S0022-5347(17)36425-X]
40. Al-Zubaidy KI. Most studies indicated that the most common cause of recurrent urinary tract infections are Escherichia coli (Bacterial Vulnerability and Blood Types, Salmonella and Escherichia coli as A study case. J Basrah Res (Sciences). 2020;46(2):74-88. [Link]
41. Najari H, Ghadimi A, Allami A. The relationship of ABO-Rh blood groups with urinary tract infections in hospitalized patients. Scientific J Kurdistan Univ Med Sci. 2020;25(4):20-30. [Link] [DOI:10.52547/sjku.25.4.20]
42. Bublitz DC, Wright PC, Bodager JR, Rasambainarivo FT, Bliska JB, Gillespie TR. Epidemiology of pathogenic enterobacteria in humans, livestock, and peridomestic rodents in rural Madagascar. PLoS One. 2014;9(7):e101456. [Link] [DOI:10.1371/journal.pone.0101456]
43. Cristea OM, Avrămescu CS, Bălășoiu M, Popescu FD, Popescu F, Amzoiu, MO. Urinary tract infection with Klebsiella pneumoniae in Patients with Chronic Kidney Disease. Curr Health Sci J. 2017;43(2):137-48. [Link]
44. Beyene G, Tsegaye W. Bacterial uropathogens in urinary tract infection and antibiotic susceptibility pattern in Jimma university specialized hospital, southwest Ethiopla. Ethiop J Health Sci. 2011;21(2):141-6. [Link] [DOI:10.4314/ejhs.v21i2.69055]
45. Muder RR, Brennen C, Rihs J, Wagener MM, Obman A, Stout JE, et al. Isolation of Staphylococcus aureus from the urinary tract: association of isolation with symptomatic urinary tract infection and subsequent staphylococcal bacteremia. Clin Infect Dis. 2006;42(1):46-50. [Link] [DOI:10.1086/498518]
46. Abdel Gawad AM, Ashry WM, El-Ghannam S, Hussein M, Yousef A. Antibiotic resistance profile of common uropathogens during COVID-19 pandemic: hospital based epidemiologic study. BMC Microbiol. 2023;23(28):1-8. [Link] [DOI:10.1186/s12866-023-02773-5]
47. Sobel JD, Kaye D. Urinary tract infections. In Mandell GL, Bennett JE editors. Principles and Practice of Infectious Diseases. 8th ed. Philadelphia: Elsevier Saunders; 2014. pp. 886-913. [Link] [DOI:10.1016/B978-1-4557-4801-3.00074-6]
48. Stapleton A, Nudelman E, Clausen H, Hakomori S, Stamm WE. Binding of uropathogenic Escherichia coli R45 to glycolipids extracted from vaginal epithelial cells is dependent on histo-blood group secretor status. J Clin Invest. 1992;90:965-72. [Link] [DOI:10.1172/JCI115973]