JMERC
Owner
Janbazan Medical and Engineering Research Center (JMERC) is the owner of IJWPH.
0.4
Cite Score
SJR: 0.114 / SNIP: 0.090
Volume 15, Issue 1 (2023)
Iran J War Public Health 2023, 15(1): 49-54 |
Back to browse issues page
Article Type:
Subject:
History
Received: 2023/01/6 | Accepted: 2023/03/6 | Published: 2023/03/16
Received: 2023/01/6 | Accepted: 2023/03/6 | Published: 2023/03/16
How to cite this article
Shafiei M, Sabouri M, Izadi F, Karimi K, Sheibani Tehrani D. Post-traumatic Epilepsy, 33 Years Following Traumatic Brain Injury: Iraq vs. Iran War. Iran J War Public Health 2023; 15 (1) :49-54
URL: http://ijwph.ir/article-1-1277-en.html
URL: http://ijwph.ir/article-1-1277-en.html
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Rights and permissions
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
1- Department of Neurosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2- Department of Neurosurgery, School of Medicine, Medical Image and Signal Processing Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
3- “Medical Image and Signal Processing Research Center“ and “Department of Neurosurgery, School of Medicine”, Isfahan University of Medical Sciences, Isfahan, Iran
4- Department of General Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
5- Department of IT, Faculty of Engineering, Shahid Beheshti University, Tehran, Iran
2- Department of Neurosurgery, School of Medicine, Medical Image and Signal Processing Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
3- “Medical Image and Signal Processing Research Center“ and “Department of Neurosurgery, School of Medicine”, Isfahan University of Medical Sciences, Isfahan, Iran
4- Department of General Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
5- Department of IT, Faculty of Engineering, Shahid Beheshti University, Tehran, Iran
Abstract (1198 Views)
Aims: Post-traumatic epilepsy is one of the most common and disabling sequels of traumatic brain injury and is defined as repeated unprovoked seizures seven days after traumatic brain injury. The present study aimed to determine the late consequences of epilepsy in veterans with traumatic brain injury during the imposed Iran-Iraq war.
Instruments & Methods: This study was observational cohort research in 2022. The sample of the study included all living veterans with a history of Post-traumatic epilepsy who were covered by the services of the "Veterans Affairs Foundation" of Isfahan, Iran. 218 veterans with epilepsy, who were available, were identified, 100 of them had a traumatic brain injury, and 118 did not have any traumatic brain injury. Data were collected using the Mini Mental State Examination (MMSE) and Instrumental Activities of Daily Living and Physical Self-Maintenance Scale (IADL-PSMS).
Findings: There was a significant difference between veterans with and without traumatic brain injuries in the age at post-traumatic epilepsy debut (p<0.05). Epilepsy characteristics were not significantly different between the two groups (p>0.05). The mean score of MMSE in veterans with and without traumatic brain injuries was significantly different (p<0.05). The Recall and Registration subscales were significantly different in veterans with/without traumatic brain injuries (p<0.05).
Conclusion: The ability to perform daily activities and cognitive function are lower in veterans with epilepsy with traumatic brain injuries compared to veterans with epilepsy without traumatic brain injuries.
Instruments & Methods: This study was observational cohort research in 2022. The sample of the study included all living veterans with a history of Post-traumatic epilepsy who were covered by the services of the "Veterans Affairs Foundation" of Isfahan, Iran. 218 veterans with epilepsy, who were available, were identified, 100 of them had a traumatic brain injury, and 118 did not have any traumatic brain injury. Data were collected using the Mini Mental State Examination (MMSE) and Instrumental Activities of Daily Living and Physical Self-Maintenance Scale (IADL-PSMS).
Findings: There was a significant difference between veterans with and without traumatic brain injuries in the age at post-traumatic epilepsy debut (p<0.05). Epilepsy characteristics were not significantly different between the two groups (p>0.05). The mean score of MMSE in veterans with and without traumatic brain injuries was significantly different (p<0.05). The Recall and Registration subscales were significantly different in veterans with/without traumatic brain injuries (p<0.05).
Conclusion: The ability to perform daily activities and cognitive function are lower in veterans with epilepsy with traumatic brain injuries compared to veterans with epilepsy without traumatic brain injuries.
Keywords:
References
1. Bandopadhyay R, Singh T, Ghoneim MM, Alshehri S, Angelopoulou E, Paudel YN, et al. Recent developments in diagnosis of epilepsy: Scope of MicroRNA and technological advancements. Biology (Basel). 2021;10(11):1097. [Link] [DOI:10.3390/biology10111097]
2. Daneshyar S, Ghiasian M, Moradi S, Khanlarzadeh E. Efficacy of levetiracetam, lamotrigine and sodium valproate on seizure attacks and EEG disorders in patients with juvenile myoclonic epilepsy: A double blind randomized clinical trial. Caspian J Intern Med. 2022;13(3):617-22. [Link]
3. Ding K, Puneet K, Diaz-Arrastia R. Epilepsy after traumatic brain injury. In: Laskowitz D, Grant G, editors. Translational research in traumatic brain injury. Boca Raton (FL): CRC Press/Taylor and Francis Group; 2016. [Link]
4. Segal AG., Rodriguez KL, Shea JA, Hruska KL, Lorrie Walker L, Groeneveld PW. Quality and value of health care in the veterans health administration: a qualitative study. J Am Heart Assoc. 2019;8(9):e011672. [Link] [DOI:10.1161/JAHA.118.011672]
5. Al Jowf GI , Ahmed ZT, An N, Reijnders RA, Ambrosino E, Rutten BPF, et al. A public health perspective of post-traumatic stress disorder. Int J Environ Res Public Health. 2022;19(11):6474. [Link] [DOI:10.3390/ijerph19116474]
6. Inoue C, Shawler E, Jordan Christopher H. Veteran and military mental health issues. StatPearls Publishing; 2022. [Link]
7. Kintzle S, Barr N, Corletto G, Castro CA. PTSD in U.S. veterans: The role of social connectedness, combat experience and discharge. Healthcare (Basel). 2018;6(3):102. [Link] [DOI:10.3390/healthcare6030102]
8. Asare-Doku W, Donnir GM, Ae-Ngibise KA, Peprah J, Awuviry-Newton K, Acquah F. Psychiatric disorders among the military in West Africa: a systematic narrative review. Behav Sci (Basel). 2021;11(10):138. [Link] [DOI:10.3390/bs11100138]
9. Griffin BA, Grimm GE, Smart R, Ramchand R, Jaycox LH, Ayer L, et al. Comparing the army's suicide rate to the general U.S. population. Rand Health Q. 2021;9(2):8. [Link]
10. Preliminary Assessment of Readjustment Needs of Veterans, Service Members, and Their Families. Returning home from Iraq and Afghanistan. Washington (DC): National Academies Press (US); 2012. [Link]
11. Kong L-Z, Zhang R-L, Hu S-H, Lai J-B. Military traumatic brain injury: a challenge straddling neurology and psychiatry. Mil Med Res. 2022;9:2. [Link] [DOI:10.1186/s40779-021-00363-y]
12. Bhattrai A, Irimia A, Van Horn JD. Neuroimaging of traumatic brain injury in military personnel: an overview. J Clin Neurosci. 2019;70:1-10. [Link] [DOI:10.1016/j.jocn.2019.07.001]
13. Fatuki TA, Zvonarev V, Rodas AW. Prevention of traumatic brain injury in the United States: significance, new findings, and practical applications. Cureus. 2020;12(10):e11225. [Link] [DOI:10.7759/cureus.11225]
14. Georges A, Das JM. Traumatic brain injury. StatPearls Publishing; 2022. [Link]
15. Keller L, Stelzle D, Schmidt V, Carabin H, Reinhold AK, Keller C, et al. Community-level prevalence of epilepsy and of neurocysticercosis among people with epilepsy in the Balaka district of Malawi: A cross-sectional study. PLoS Negl Trop Dis. 2022;16(9):e0010675. [Link] [DOI:10.1371/journal.pntd.0010675]
16. Brady RD, Casillas-Espinosa PM, Agoston DV, Bertram EH, Kamnaksh A, Semple BD, et al. Modelling traumatic brain injury and posttraumatic epilepsy in rodents. Neurobiol Dis. 2019;123:8-19. [Link] [DOI:10.1016/j.nbd.2018.08.007]
17. Fordington S, Manford M. A review of seizures and epilepsy following traumatic brain injury. J Neurol. 2020;267(10):3105-11. [Link] [DOI:10.1007/s00415-020-09926-w]
18. Anwer F, Oliveri F, Kakargias F, Panday P, Franchini APA, Iskander B, et al. Post-traumatic seizures: a deep-dive into pathogenesis. Cureus. 2021;13(4):e14395. [Link] [DOI:10.7759/cureus.14395]
19. Fiest KM, Sauro KM, Wiebe S, Patten SB, Kwon CS, Dykeman J, et al. Prevalence and incidence of epilepsy: A systematic review and meta-analysis of international studies. Neurology. 2017;88(3):296-303. [Link] [DOI:10.1212/WNL.0000000000003509]
20. Sayehmiri K, Tavan H, Sayehmiri F, Mohammadi I, Carson KV. Prevalence of epilepsy in Iran: A meta-analysis and systematic review. Iran J Child Neurol. 2014;8(4):9-17. [Link]
21. Rehman R, Kelly PR, Husain AM, Tran TT. Characteristics of veterans diagnosed with seizures within Veterans Health Administration. J Rehabil Res Dev. 2015;52(7):751-62. [Link] [DOI:10.1682/JRRD.2014.10.0241]
22. Frey LC. Epidemiology of posttraumatic epilepsy: a critical review. Epilepsia. 2003;44(Suppl. 10):11-7. [Link] [DOI:10.1046/j.1528-1157.44.s10.4.x]
23. Pitkänen A, Immonen R. Epilepsy related to traumatic brain injury. Neurotherapeutics. 2014;11(2):286-96. [Link] [DOI:10.1007/s13311-014-0260-7]
24. Salinsky M, Rutecki P, Parko K, Goy E, Storzbach D, Markwardt S, et al. Health-related quality of life in Veterans with epileptic and psychogenic nonepileptic seizures. Epilepsy Behav. 2019;94:72-7. [Link] [DOI:10.1016/j.yebeh.2019.02.010]
25. Pugh MJV, Berlowitz DR, Kazis L. The impact of epilepsy on older veterans. Int Rev Neurobiol. 2007;81:221-33. [Link] [DOI:10.1016/S0074-7742(06)81014-7]
26. Pugh MJ, Kennedy E, Gugger JJ, Mayo J, Tate D, Swan A, et al. The military injuries: Understanding post-traumatic epilepsy study: understanding relationships among lifetime traumatic brain injury history, epilepsy, and quality of life. J Neurotrauma. 2021;38(20):2841-50. [Link] [DOI:10.1089/neu.2021.0015]
27. Karlander M, Ljungqvist J, Zelano J. Post-traumatic epilepsy in adults: a nationwide register-based study. J Neurol Neurosurg Psychiatry. 2021;92(6):617-21. [Link] [DOI:10.1136/jnnp-2020-325382]
28. Mackin SR, Tosun D, Mueller SG, Lee JY, Insel P, Schuff N, et al. Patterns of reduced cortical thickness in late-life depression and relationship to psychotherapeutic response. Am J Geriatr Psychiatry. 2013;21(8):794-802. [Link] [DOI:10.1016/j.jagp.2013.01.013]