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Received: 2026/10/10 | Accepted: 2026/11/12
Received: 2026/10/10 | Accepted: 2026/11/12
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Authors
Luay asaad Mahmood, Mithal R. Alkubaisi *1, Noor Thair Tahir, Marwah Mohammed Nasri, Raghda Shams Akram
1- , mithalreadh@uoanbar.edu.iq
Abstract (4 Views)
The majority of adults worldwide suffer from musculoskeletal (MSK) disorders, which are extremely common and cause crippling pain. MSK symptoms typically appear in midlife, and there is evidence that they may be connected to the menopausal transition and the corresponding drop in estrogens. The purpose of this research is to examine how vitamin D3 insufficiency and parathyroid hormone (PTH) affect metabolic changes in menopausal women. Ninety Iraqi women diagnosed as menopause women with musculoskeletal and type 2 diabetes mellitus their age range was (45-55) years. there was shown a highly significant increase of HbA1C, FBS,TC and LDL between groups (Menopause Diabetic women with Musculoskeletal Manifestations and control) . While a highly significant decrees of HDL-C between groups (Menopause Diabetic women with Musculoskeletal Manifestations and control). A highly significant increase of estrogen, LH, FSH,Ca and PTH between groups (Menopause Diabetic women with Musculoskeletal Manifestations and control) . While a highly significant decrees of D3 between groups (Menopause Diabetic women with Musculoskeletal Manifestations and control). It can conclusion that menopausal diabetic women with hyperparathyroidism may be more susceptible to musculoskeletal symptoms because the vitamin D3–PTH–calcium axis is disrupted. Impaired bone and muscular function may be caused by vitamin D3 deficiency and raised PTH, underscoring the significance of early metabolic evaluation and treatment.
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