Jasim D, Mohammed W. Social Support as a Mediator between Resilience and Quality of Life among Patients Receiving Chemotherapy for Gastrointestinal Cancer. Iran J War Public Health 2025; 17 (3) :1001-1006 URL: http://ijwph.ir/article-1-1620-en.html
Background: Gastrointestinal cancer is among the most prevalent malignancies. Cancer statistics indicate that GI cancers represent 38% of all cancer cases. Chemotherapy for GI cancer can significantly impact patients' quality of life. Resilience plays a crucial role in overcoming these challenges. Social support from family and friends can improve patients' ability to handle with the impact of therapy. This study examines the mediating role of social support in the relationship between resilience and quality of life. Method: A descriptive cross-sectional study design was conducted among 275 GI cancer Patients at three Iraqi governorates with a purposive sampling method, from October 2024 to April 2025. Data was collected used demographic and clinical characteristics questionnaire, Connor-Davidson Resilience Scale(CD-RISC10), European Organization for Research and Treatment of Cancer Quality of Life (EORTC QLQ-F17), and Multidimensional Scale of Perceived Social scales(MSPSS-12). Results: The mean of resilience was (22.84), reflecting a generally low level of psychological resilience; the mean of perceived social support was (44.62), indicating that more than half of participants had a high level of perceived social support, and the mean general quality of life was (47.4331), reflecting a relatively poor ability to adapt to health conditions. The total effect of resilience on quality of life was (0.7227), the direct effect value was (0.4031), and the indirect effect via social support was (0.3196). Conclusions: social support mediates the relationship between psychological resilience and quality of life. This role improves psychological resilience and, thus, enhances the quality of life for cancer patients.