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Volume 16, Issue 1 (2024)
Iran J War Public Health 2024, 16(1): 1001-1009 |
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Received: 2023/11/7 | Accepted: 2024/03/4 | Published: 2024/03/28
Received: 2023/11/7 | Accepted: 2024/03/4 | Published: 2024/03/28
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Zainab m.Jaafar m.saeed, Hameed Jaafar, Sarah Hassan abdulshaheed Alburkiebh. Effect of nebulized lidocaine and Intravenous lidocaine on hemodynamic responses of laryngoscopy and endotracheal intubation. Iran J War Public Health 2024; 16 (1) :1001-1009
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1- Faculty of Pharmacy.kufa UniversityJaafar
2- Medical College kufa university
3- Ministry of health
2- Medical College kufa university
3- Ministry of health
Abstract (175 Views)
Aims: To find the most effective way of lidocaine administration in attenuation of hemodynamic response to laryngoscopy and endotracheal intubation.
Patients and method : A 78 patients categorized into 3 groups, control (C) group of 26 patients received 5 ml of IV normal saline with the induction drugs, intravenous lidocaine (IVL) group of 26 cases received 1.5 mg/kg 2% IV lidocaine 2 minutes prior to laryngoscopy and intubation while nebulized lidocaine (NL) group 0f 26 cases received a 4 ml of 2% lidocaine nebulized by cirrus nebulizer with 5 L/min oxygen flow which usually takes from 10 to 15 minutes then induction immediately started.
Results : Among the 3 groups, demographic data shows no significant difference.
Comparing the C and NL group there is significant difference between them in advantage of lidocaine nebulizer for hemodynamic response attenuation, in C and IVL group comparison there is significant difference in some readings which reflects incomplete blunting effect. So lidocaine nebulizer shows a better results of cardiovascular stability.
Conclusion: Nebulized lidocaine found to be significantly effective in attenuation of hemodynamic changes that accompany direct laryngoscopy and endotracheal intubation.
Patients and method : A 78 patients categorized into 3 groups, control (C) group of 26 patients received 5 ml of IV normal saline with the induction drugs, intravenous lidocaine (IVL) group of 26 cases received 1.5 mg/kg 2% IV lidocaine 2 minutes prior to laryngoscopy and intubation while nebulized lidocaine (NL) group 0f 26 cases received a 4 ml of 2% lidocaine nebulized by cirrus nebulizer with 5 L/min oxygen flow which usually takes from 10 to 15 minutes then induction immediately started.
Results : Among the 3 groups, demographic data shows no significant difference.
Comparing the C and NL group there is significant difference between them in advantage of lidocaine nebulizer for hemodynamic response attenuation, in C and IVL group comparison there is significant difference in some readings which reflects incomplete blunting effect. So lidocaine nebulizer shows a better results of cardiovascular stability.
Conclusion: Nebulized lidocaine found to be significantly effective in attenuation of hemodynamic changes that accompany direct laryngoscopy and endotracheal intubation.