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Volume 14, Issue 2 (2022)
Iran J War Public Health 2022, 14(2): 225-230 |
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Received: 2022/04/9 | Accepted: 2022/06/20 | Published: 2022/06/25
Received: 2022/04/9 | Accepted: 2022/06/20 | Published: 2022/06/25
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Najim Rasool R, Aboud Khalifa A. Studying the Role of Interleukin-6, C-Reactive Protein, and Nitric Oxide Synthase in Obese, Diabetic, and Sub-Fertile Men. Iran J War Public Health 2022; 14 (2) :225-230
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R. Najim Rasool *1, A. Aboud Khalifa1
1- Department of Biology, College of Science, University of Misan, Maysan, Iraq
Abstract (1550 Views)
Aims: This study aimed to investigate the role of Interleukin-6, C-reactive protein, and Nitric oxide synthase in obese, diabetic, and sub-fertile men.
Material & Methods: The current study was conducted in some health centers in Misan province, Iraq, from December 2020 to July 2021. The whole sample included 80 men aged 35-45 years, divided into four groups (20 men/group). Eight to ten milliliters of venous blood samples were drawn at 9 - 11 am, using a disposable needle and plastic syringes for each man. The blood was left at room temperature for 15 minutes for coagulation, centrifuged at 3000rpm for 5 minutes, then serum and plasma were separated and transferred for storage. Statistical analysis was performed by IBM SPSS 23 using ANOVA.
Findings: Results revealed: Interleukin-6 increased significantly (p<0.05), except in the diabetic group, in different groups in comparison with the control, C-reactive protein increased significantly (p<0.05) in different groups in comparison with the control, Nitric oxide synthase decreased significantly (p<0.05), except in sub-fertility group, in different groups in comparison with the control.
Conclusion: The Interleukin-6 and C-reactive protein increment and Nitric oxide synthase reduction in different groups might be indicated a pro-inflammatory action and low fertility in obesity, diabetic and sub-fertility groups.
Material & Methods: The current study was conducted in some health centers in Misan province, Iraq, from December 2020 to July 2021. The whole sample included 80 men aged 35-45 years, divided into four groups (20 men/group). Eight to ten milliliters of venous blood samples were drawn at 9 - 11 am, using a disposable needle and plastic syringes for each man. The blood was left at room temperature for 15 minutes for coagulation, centrifuged at 3000rpm for 5 minutes, then serum and plasma were separated and transferred for storage. Statistical analysis was performed by IBM SPSS 23 using ANOVA.
Findings: Results revealed: Interleukin-6 increased significantly (p<0.05), except in the diabetic group, in different groups in comparison with the control, C-reactive protein increased significantly (p<0.05) in different groups in comparison with the control, Nitric oxide synthase decreased significantly (p<0.05), except in sub-fertility group, in different groups in comparison with the control.
Conclusion: The Interleukin-6 and C-reactive protein increment and Nitric oxide synthase reduction in different groups might be indicated a pro-inflammatory action and low fertility in obesity, diabetic and sub-fertility groups.
Keywords:
Interleukin-6 [MeSH], C - Reactive Protein [MeSH], Nitric Oxide Synthase [MeSH], Obesity [MeSH], Diabetes [MeSH], Subfertility [MeSH]
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