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Volume 14, Issue 4 (2022)
Iran J War Public Health 2022, 14(4): 401-408 |
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Article Type:
Descriptive & Survey
Subject:
History
Received: 2022/08/23
Accepted: 2022/11/11
Published: 2022/11/1
Accepted: 2022/11/11
Published: 2022/11/1
How to cite this article
Jumagaliyeva M, Ayaganov D, Saparbayev S, Tuychibayeva N. Hypoxic Encephalopathy in COVID-19. Iran J War Public Health 2022; 14 (4) :401-408
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URL: http://ijwph.ir/article-1-1263-en.html
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1- Department of Neurology with the Course of Psychiatry and Narcology, Faculty of General Medicine, West Kazakhstan Marat Ospanov Medical University, Aktobe, Republic of Kazakhstan
2- West Kazakhstan Marat Ospanov Medical University, Aktobe, Republic of Kazakhstan
3- Department of Neurology with a Course of Medical Psychology and Psychotherapy, Medical Faculty, Tashkent Medical Academy, Tashkent, Republic of Uzbekistan
2- West Kazakhstan Marat Ospanov Medical University, Aktobe, Republic of Kazakhstan
3- Department of Neurology with a Course of Medical Psychology and Psychotherapy, Medical Faculty, Tashkent Medical Academy, Tashkent, Republic of Uzbekistan
* Corresponding Author Address: 68 Maresyev Str., Aktobe, Republic of Kazakhstan. Postal Code: 030012 (merey.jumagaliyeva@gmail.com)
Abstract (805 Views)
Aims: This study aimed to investigate the prevalence of hypoxic encephalopathy in patients with COVID-19 and its relationship with in-hospital mortality.
Instruments & Methods: A multicenter prospective study was conducted on 1277 patients with SARS-CoV-2 infection. All patients were evaluated based on age, severity of disease course, presence or absence of typical symptoms of COVID-19, presence of exacerbating chronic conditions, and presence of developed acute neurological complications. Patients with signs of encephalopathy were identified among patients with acute neurological complications, and a differential diagnosis was carried out to identify hypoxic encephalopathy. The data relating to severe patients with hypoxic COVID-19-associated encephalopathy was studied thoroughly for the chronology of the onset of symptoms, detection of the SARS-CoV-2, the similarity of test results, and diagnostic clinical examinations.
Findings: Hypoxic encephalopathy was identified as the most severe complication among patients with neurological disorders. Most often, older patients had a severe course of the disease. 20% of patients had obtained disorders of the nervous system. 92% of them were diagnosed with hypoxic encephalopathy, which led to death in 95% of cases.
Conclusion: SARS-CoV-2 hypoxic encephalopathy may lead to a poor prognosis for the course of the disease in the vast majority of patients with neurological complications. It means that this serious complication should be investigated more carefully for possible prevention, early diagnosis, effective treatment, and long-term rehabilitation for patients with COVID-19.
Instruments & Methods: A multicenter prospective study was conducted on 1277 patients with SARS-CoV-2 infection. All patients were evaluated based on age, severity of disease course, presence or absence of typical symptoms of COVID-19, presence of exacerbating chronic conditions, and presence of developed acute neurological complications. Patients with signs of encephalopathy were identified among patients with acute neurological complications, and a differential diagnosis was carried out to identify hypoxic encephalopathy. The data relating to severe patients with hypoxic COVID-19-associated encephalopathy was studied thoroughly for the chronology of the onset of symptoms, detection of the SARS-CoV-2, the similarity of test results, and diagnostic clinical examinations.
Findings: Hypoxic encephalopathy was identified as the most severe complication among patients with neurological disorders. Most often, older patients had a severe course of the disease. 20% of patients had obtained disorders of the nervous system. 92% of them were diagnosed with hypoxic encephalopathy, which led to death in 95% of cases.
Conclusion: SARS-CoV-2 hypoxic encephalopathy may lead to a poor prognosis for the course of the disease in the vast majority of patients with neurological complications. It means that this serious complication should be investigated more carefully for possible prevention, early diagnosis, effective treatment, and long-term rehabilitation for patients with COVID-19.
Keywords:
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