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Volume 14, Issue 3 (2022)
Iran J War Public Health 2022, 14(3): 331-337 |
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Received: 2022/05/31 | Accepted: 2022/08/26 | Published: 2022/10/11
Received: 2022/05/31 | Accepted: 2022/08/26 | Published: 2022/10/11
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Meryud Abood A, Mohammud Habash M, Mohammed M. Epidemiology of Colonic Cancer in Baghdad City, Iraq. Iran J War Public Health 2022; 14 (3) : 12
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1- Department of Surgery, College of Medicine, University of Diyala, Diyala, Iraq
2- Department of Anesthesia, College of Diyala, Bilad Alrafidain University, Diyala, Iraq
2- Department of Anesthesia, College of Diyala, Bilad Alrafidain University, Diyala, Iraq
Abstract (800 Views)
Aims: Colonic carcinoma is the most commonly diagnosed cancer-related morbidity and mortality worldwide with high mortality. It is the third most common among all cancer types. This study aimed to evaluate the correlation among various colonic subset distributions, their stages, grade, surgical management, and complication of colonic carcinoma.
Materials & Methods: This prospective study was conducted at Gastroenterology and Hepatology teaching hospital, in Baghdad, Iraq, from November 2014 to February 2016. 74 patients (43 males and 31 females) were selected. All specimens were sent for a histopathology examination. The data from physical examination, investigations, and operatives were used in the Duke’s staging system. The collected data were analyzed in SPSS 19 software.
Findings: The male-to-female ratio was found to be 1.38:1 a peak age of incidence in the seventh decade. Both showed the maximum incidence numbers after 50 years of age. The main presenting symptom was abdominal pain 70%. The mean period between the onset of presenting symptoms and the final diagnosis was 7 months. The most common sites were recto-sigmoid junction (22.9%) forty eight had a high grade differentiated and 41% were Duke's B2.
Conclusion: Males are more prone to get CC than females between 50 and 60 years. Right colon cancer is more prevalent in Iraqi patients.
Materials & Methods: This prospective study was conducted at Gastroenterology and Hepatology teaching hospital, in Baghdad, Iraq, from November 2014 to February 2016. 74 patients (43 males and 31 females) were selected. All specimens were sent for a histopathology examination. The data from physical examination, investigations, and operatives were used in the Duke’s staging system. The collected data were analyzed in SPSS 19 software.
Findings: The male-to-female ratio was found to be 1.38:1 a peak age of incidence in the seventh decade. Both showed the maximum incidence numbers after 50 years of age. The main presenting symptom was abdominal pain 70%. The mean period between the onset of presenting symptoms and the final diagnosis was 7 months. The most common sites were recto-sigmoid junction (22.9%) forty eight had a high grade differentiated and 41% were Duke's B2.
Conclusion: Males are more prone to get CC than females between 50 and 60 years. Right colon cancer is more prevalent in Iraqi patients.
Article number: 12
Keywords:
References
1. AL-Bahrany Zuhair R, Dezzay O, Alkhateeb AK, Butrous GS. Cancer of colon and rectum in Iraq. Am J Proct Gastro Colon Resct Surg. 1980;1:20-2. [Link]
2. Al Dahhan SA, Al Lami FH. Epidemiology of colorectal cancer in Iraq, 2002-2014. Gulf J Oncol. 2018;1(26):23-6. [Link]
3. Al-Saigh THT, Al-Bayati SA, Abdulmawjood SA, Ahmed FA. Descriptive study of colorectal cancer in iraq, 1999-2016. Ann Coll Med Mosul. 2019;41(1):81-5. [Link] [DOI:10.33899/mmed.2019.161330]
4. American Cancer Society. Global cancer facts and figures. 4th Edition. Atlanta: American Cancer Society Inc.; 2018. [Link]
5. Astler VB, Coller FA. The prognostic significance of direct extension of carcinoma of the colon and rectum. Ann Surg. 1954;139(6):846-52. [Linkv] [DOI:10.1097/00000658-195406000-00015]
6. Bakeri AA. Clinicopathologica pattern and challenge in the management of colorectal cancer in sub-Saharan Africa. J Chines Clin Med. 2007;21(121):20-5. [Link]
7. Berube S, Diorio C, Masse B, Hebert-Croteau N, Byrne C, Cote G, et al. Vitamin D and calcium intakes from food or supplements and mammographic breast density. Cancer Epidemiol Biomarkers Prev, 2005;14(7):1653-9. [Link] [DOI:10.1158/1055-9965.EPI-05-0068]
8. Binkert C A, Ledermann H, Jost R, Saurenmann P, Decurtins M, Zollikofer CL. Acute colonic obstruction: Clinical aspects and cost-effectiveness of preoperative and palliative treatment with self-expanding metallic stents--a preliminary report. Radiology. 1998;206(1):199-204. [Link] [DOI:10.1148/radiology.206.1.9423673]
9. Bosetti C, Bertuccio P, Malvezzi M, Levi F, Chatenoud L, Negri E, et al. Cancer mortality in Europe, 2005‑ 2009, and an overview of trends since 1980. Ann Oncol. 2013;24(10):2657-71. [Linkvvv] [DOI:10.1093/annonc/mdt301]
10. Boyle P, Langman JS. Epidemiology. BMJ. 2000;321(7264):805‑8. [Link] [DOI:10.1136/bmj.321.7264.805]
11. Boyle P, Leon ME. Epidemiology of colorectal cancer. Br Med Bull. 2002;64(1):1‑25. [Link] [DOI:10.1093/bmb/64.1.1]
12. Brozek W, Kriwanek S, Bonner E, Peterlik M, Cross H. Mutual associations between malignancy, age, gender, and subsite incidence of colorectal cancer. Anticancer Res. 2009;29(9):3721-6. [Link]
13. Bruce E. Jarrel, R. National medical series for independent study-surgery. 4th Edition. Philadelphia: Lippincott William & Wilkins; 2000. pp. 234-40. [Link]
14. Cairns S, Scholfield JH. Guidelines for colorectal cancer screening in high-risk groups. Gut. 2002;51(Suppl 5):V1-2. [Link] [DOI:10.1136/gut.51.suppl_5.v1]
15. Calle EE, Miracle-McMahill HL, Thun MJ, Heath CW. Estrogen replacement therapy and risk of fatal colon cancer in a prospective cohort of postmenopausal women. J Natl Cancer Inst. 1995;87(7):517-23. [Link] [DOI:10.1093/jnci/87.7.517]
16. Chattar-Cora D, Onime GD, Coppa GF, Valentine IS, Rivera L. Anatomic, age, and sex distribution of colorectal cancer in a New York City hispanic population. J Natl Med Assoc. 1998;90(1):19-24. [Link]
17. Cho VR, Vogelstein B. Colorectal cancer-genetic alterations in the adenoma-carcinoma sequence. Cancer. 1992;70(Suppl 6):1727-31.
https://doi.org/10.1002/1097-0142(19920915)70:4+<1727::AID-CNCR2820701613>3.0.CO;2-P [Link] [DOI:10.1002/1097-0142(19920915)70:4+3.0.CO;2-P]
18. Corman MI, Allison SI, Kuehene JP. Hand book of colon and rectal surgery. Philadelphia PA: Lippincott, Williams and Wilkins; 2002. pp. 518-21. [Link]
19. Doğusoy G. Kolon Kanserinin Patolojik Özellikleri. In: Alemdaroğlu K, Akçal T, Buğra D, editors. Kolon Rektum ve Anal Bölge Hastalıkları. İstanbul: Türk Kolon ve Rektum Cerrahi Derneği; 2003. pp. 413-20. [Turkish] [Link]
20. Dukes CE. The classification of cancer of the rectum. J Pathol Bacteriol. 1932;35(3):323-32. [Link] [DOI:10.1002/path.1700350303]
21. El-Hasseni MB. The changing pattern of cancer in Iraq during the last 18 years. Baghdad: Ministry of Health Iraqi Cancer Board; 1999. [Link]
22. Elzouki AN, Habel S, Alsoaeiti S, Abosedra A, Khan F. Epidemiology and clinical findings of colorectal carcinoma in two tertiary care hospitals in Benghazi, Libya. Avicenna J Med. 2014;4(4)-94-8. [Link] [DOI:10.4103/2231-0770.140659]
23. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990;61(5):759-67. [Link] [DOI:10.1016/0092-8674(90)90186-I]
24. Garcia-Anguilar J, Mellgren A, Sirivangs P, Buie D, Madoff RD, Rothenberger DA. Local excision of rectal cancer without adjuvant therapy: A word of caution. Ann Surg. 2000;231(3):345-51. [Link] [DOI:10.1097/00000658-200003000-00007]
25. Gericke D. Early diagnosis saves human life on the status of colorectal tumors. Versicherungsmedizin. 1992;44(2):60-3. [German] [Linkv]
26. Grigg M, McDermott FT, Pihl EA, Hughes ES. Curative local excision in the treatment of carcinoma of the rectum. Dis Colon Rectum. 1984;27(2):81-3. [Link] [DOI:10.1007/BF02553979]
27. Grodstein F, Newcomb PA, Stampfer MJ. Postmenopausal hormone therapy and the risk of colorectal cancer: A review and meta-analysis. Am J Med. 1999;106(5):574-82. [Link] [DOI:10.1016/S0002-9343(99)00063-7]
28. Halder SK, Bhattacharjee PK, Bahr P, Pachaury A. Epidemiological, clinico-pathological profile and management of colorectal carcinoma in a tertiary referral center of eastern India. J Krishna Ins Med Sci Univ. 2013;2(1):45-50 [Link]
29. Hassan HA, Sameen AN. Colorectal carcinoma, presentation and pattern of surgical management at the university hospital [dissertation]; 2002. [Link]
30. Huddy SP, Husband EM, Cook MG, Gibbs NM, Marks CG, Heald RJ. Lymph node metastasis in early rectal cancer. Br J Surg. 1993;80(11):1458-8. [Link] [DOI:10.1002/bjs.1800801135]
31. Ibrahem S, Ahmed H, Zangana S. Trends in colorectal cancer in Iraq over two decades: Incidence, mortality, topography and morphology. Ann Saudi Med. 2022;42(4):252-61. [Link] [DOI:10.5144/0256-4947.2022.252]
32. Iraqi Cancer Board. A report of the results of the Iraqi cancer registry from 1995 to 1997. Baghdad: Ministry of Health Publishing; 1999. [Arabic] [Link]
33. Jacobs EJ, White E, Weiss NS. Exogenous hormones, reproductive history, and colon cancer (Seattle, Washington, USA). Cancer Causes Control. 1994;5(4):359-66. [Link] [DOI:10.1007/BF01804987]
34. Janout V, Kollarova H. Epidemiology of colorectal cancer 2001. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2001;145(1):5-10. [Link] [DOI:10.5507/bp.2001.001]
35. Jarvinen HJ, Ovaska J, Meklin JP. Improvment in treatment and prognosis of colorectal carcinoma. Br J Surg. 1988;75(1):25-7. [Link] [DOI:10.1002/bjs.1800750110]
36. Jemal A, Center MM, DeSantis C, Ward EM. Global patterns of cancer incidence and mortality rates and trends. Cancer Epidemiol Biomarkers Prev. 2010;19(8):1893‑907. [Link] [DOI:10.1158/1055-9965.EPI-10-0437]
37. Jensen OM. Different age and sex relationship for cancer of subsites of the large bowel. Br J Cancer. 1984;5(6):825-9. [Link] [DOI:10.1038/bjc.1984.262]
38. Kim G, Baik SH, Lee KY, Hur H, Min BS, Lyu CJ, et al. Colon carcinoma in childhood: Review of the literature with four case reports. Int J Colorectal Dis. 2013;28(2):157-64. [Link] [DOI:10.1007/s00384-012-1603-7]
39. Kuipers EJ, Rösch T, Bretthauer M. Colorectal cancer screening--optimizing current strategies and new directions. Nat Rev Clin Oncol. 2013;10(3):130-42. [Link] [DOI:10.1038/nrclinonc.2013.12]
40. Kumar A, Daga R, Vijayaragavan P, Prakash A, Singh RK, Behari A, et al. Anterior resection for rectal carcinoma risk factors for anastomotic leaks and strictures. World J Gastroenterol. 2011;17(11):1475-79. [Link] [DOI:10.3748/wjg.v17.i11.1475]
41. Kumar V, Robbins S, Cotran R, editors. Temel Patoloji. Istanbul: Nobel Tıp Kitabevleri; 2000. pp. 505-14. [Turkish] [Link]
42. Lefebure B, Tuech JJ, Bridoux V, Costaglioli B, Scotte M, Teniere P, et al. Evaluation of selective defunctioning stoma after low anterior resection for rectal cancer. Int J Colorectal Dis. 2008;23(23):283-8. [Link] [DOI:10.1007/s00384-007-0380-1]
43. Lieberman DA, Weiss DG, Bond JH, Ahnen DJ, Garewal H, Cheifec G. Use of colonoscopy to screen asymptomatic adult for colorectal cancer. veterans affairs cooperative study group 380. N Engl J Med. 2000;343(3):162-8. [Link] [DOI:10.1056/NEJM200007203430301]
44. Lin J, Manson JE, Lee IM, Cook NR, Buring JE, Zhang SM. Intakes of calcium and vitamin D and breast cancer risk in women. Arch Intern Med. 2007;167(10):1050-9. [Link] [DOI:10.1001/archinte.167.10.1050]
45. McMichael AJ, Potter JD. Reproduction, endogenous and exogenous sex hormones, and colon cancer: A review and hypothesis. J Natl Cancer Inst. 1980;65(6):1201-7. [Link]
46. Nabi U, Nagi AH, Riaz S, Sami W. Morphological evaluation of colorectal carcinoma with grading staging and histological types. J Pak Med Assoc. 2010;60(12):998-1001. [Link]
47. Neil J. The small and large intestines. O'Connell PR, Williams NS, McCaskie AW, editors. Bailey & love's short practice of surgery. 26th Edition. Boca Raton, Florida: CRC Press; 2012. []
48. O'Connell JB, Maggard MA, Liu JH, Etzioni DA, Livingston EH, Ko CY. Rates of colon and rectal cancers are increasing in young adults. Am Surg. 2003;69(10):866‑72. []
49. Parkin DM, Pisani P, Ferlay J. Global cancer statistics. CA Cancer J Clin .1999;49:33‑64. [Link] [DOI:10.3322/canjclin.49.1.33]
50. Petrović T, Breberina M, Radovanović Z, Nikolić I, Ivković-Kapicl T. The results of the surgical treatment of rectal cancer. Arch Oncol. 2010;18(3):51-5. [Link] [DOI:10.2298/AOO1003051P]
51. Rahman MM, Al-Janabyi KA. The pattern of colorectal and anal tumor and its surgical treatment 1999. J Fac Med Baghdad. 2000;(1):38-44. [Link]
52. Sarraf S, Abdul-Jabbar A. Clinical course of colorectal cancer in young patients comparing with old patients [dissertation]; 1997. [Link]
53. Shahrudin MD, Noori SM. Cancer of the colon and rectum in the first three decades of life. HepatoGastroentrology. 1997;44(14):441-4. [Link]
54. Vasen HFA, Tomlinson I, Castells A. Clinical management of hereditary colorectal cancer syndromes. Nat Rev Gastroenterol Hepatol. 2015;12(2):88-97. [Link] [DOI:10.1038/nrgastro.2014.229]
55. Vone J R, Botting RM. Mechanism of action of asperin-like drugs. Semin Arthritis Rheum. 1997;26(6 Suppl 1):2-10. [Link] [DOI:10.1016/S0049-0172(97)80046-7]
56. Waseem T. Colorectal carcinoma presentation and manegment [dissertation]; 2009. [Link]