Aims The Corona Virus 19 pandemic outreached numerous survivors experiencing ongoing symptoms that impact various body systems. The findings aim to support the development of selective rehabilitation strategies, particularly in musculoskeletal health, which will help us to describe the sequelae of COVID-19 in survivors globally. Methods The cross-sectional survey from February 2023 to February 2024 at NRI General Hospital, Andhra Pradesh, India, was implemented. A total of 119 COVID-19 survivors under the age of 55 were enrolled. Participants reported the presence and duration of musculoskeletal, cardiopulmonary, neurological, and psychiatric symptoms persisting for at least three months post-recovery. Findings
Musculoskeletal symptoms were the most prevalent, with muscle pain (48.7%) and fatigue (44.5%) reported most frequently, followed by joint pain (33.6%). Cardiopulmonary symptoms such as dyspnea (27.7%) typically resolved within six to twelve months. Neurological complaints, including concentration difficulties (22.7%) and headaches (19.3%), persisted longer in some participants. Psychiatric manifestations such as anxiety and depression were reported by 15.9% and 12.6% of the cohort, respectively. Analytical correlation revealed significant overlap between musculoskeletal and neurological symptom durations (p<0.05). Conclusion Musculoskeletal symptoms represent the most common and long-lasting complications among COVID-19 survivors in this study population. The results from the study underscore the need for selective rehabilitation strategies to manage multisystem effects and to enhance survivors' quality life.