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Iran J War Public Health 2022, 14(3): 257-262 Back to browse issues page
Peculiarities of Clinical and Morphological Characteristics of Patients on the Local-advanced Malignant Tumors of the Thyroid Gland
I. Deineko *
Endocrine Surgery Center, Dnipropetrovsk Regional Clinical Hospital named after. І.І. Mechnikov, Dnipro, Ukraine , deineko9246@uohk.com.cn
Abstract:   (367 Views)
Aims: The main purpose of the study is to study and compare clinical and morphological characteristics, as well as the results of comprehensive treatment of patients with locally advanced malignant thyroid tumors T4a and T4b stage, compared with tumors without T1-3 invasions, to determine the main factors influencing the prognosis disease.
Material & Methods: The study groups included 120 patients with invasive locally-advanced malignant tumors of the thyroid gland of category T4a and 35 patients of category T4b. Also, for comparison of general and morphological characteristics, the control group of patients with non-invasive locally-advanced malignant tumors of the thyroid gland, or with the initial invasion of pre-thyroid muscles of category T1-3, which made up 1985 patients, was studied.
Findings: It was found that depending on the prevalence and degree of tumor invasion, the average age of patients increased, the number of men in groups increased, and the number of patients with regional and distant metastases increased, which worsened the prognosis. The most frequent localization of the invasion of the tumor of the thyroid gland was the invasion in the upper respiratory tract, namely, the invasion in the trachea, due to the close location of the thyroid gland around the trachea.
Conclusion: Aggressive surgical interventions in complex treatment allows in cases of well-differentiated tumors to significantly improve survival rates and reduce recurrence. Also, the use of radical methods of surgery improved the efficiency of treatment of the moderately differentiated tumors of the thyroid gland. Not looking at the use of aggressive radical surgery in the complex treatment of patients, the worst indicators remain in cases of moderate and poorly differentiated forms of the disease, but significantly improved quality and life expectancy, which is also important in cases of low morphological structure.
 
Article number: 2
Keywords: Thyroid Cancer, Invasion into Organs and Main Vessels of Neck and Mediastinum, Expected Response to Treatment
Full-Text [PDF 509 kb]   (232 Downloads)    
Article Type: Original Research | Subject: Diagnosis and Treatment of Veterans or Handicapped Diseases
Received: 2022/03/21 | Accepted: 2022/05/27 | Published: 2022/07/1
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Deineko I. Peculiarities of Clinical and Morphological Characteristics of Patients on the Local-advanced Malignant Tumors of the Thyroid Gland. Iran J War Public Health 2022; 14 (3) :257-262
URL: http://ijwph.ir/article-1-1177-en.html


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Volume 14, Issue 3 (2022) Back to browse issues page
مجله طب جانباز Iranian Journal of War and Public Health
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