Iranian Journal of War and Public Health

eISSN (English): 2980-969X
eISSN (Persian): 2008-2630
pISSN (Persian): 2008-2622
JMERC
0.3
Volume 13, Issue 4 (2021)                   Iran J War Public Health 2021, 13(4): 255-259 | Back to browse issues page

Print XML PDF HTML Full-Text (HTML)

History

How to cite this article
Jasim Abdullah Y, Hasan N, Zghair Jaber Alsaedi R. Correlation between Helicobacter pylori Infection and COVID-19. Iran J War Public Health 2021; 13 (4) :255-259
URL: http://ijwph.ir/article-1-1028-en.html
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rights and permissions
1- Amara Medical Institute, Southern Technical University, Amara, Iraq
2- Department of Radiological Technique, Health and Medical Technical College, AL_Zahraa University for ‎Women,‎‏ ‏Iraq
* Corresponding Author Address: Southern Technical University, Amara Technical Institute, Amara, Iraq. Postal code: 62001 (younusjasim@stu.edu.iq)
Abstract   (1499 Views)
Aims: COVID-19 and Helicobacter pylori are pathogens associated with the most common viral and bacterial infections globally. The coinfection of pathogenic bacteria and COVID-19 represented a true health challenge. The current study aimed to estimate the incidence of H. pylori in patients with COVID-19.
Materials & Methods: This experimental study was conducted in Karbalaa's COVID-19 Isolation Center from Feb. 2021 to July 2021, 130 COVID-19 patients were entered the study. A control group of 130 seemingly healthy people of similar ages and sexes was also enlisted in this research. COVID-19-infected patients were confirmed by Reverse Transcription-Polymerase Chain Reaction device. The samples were processed for total WBCs, and neutrophils were automatically computed. Data were analyzed using SPSS 21 software by independent T and Chi-square tests.
Findings: COVID-19 infection was more frequent in males than females, especially between 15 and 25 years. The COVID-19 patients were detected to have increased neutrophils count (p<0.0001) and decreased lymphocytes compared to the healthy persons (p<0.0001). A significant correlation between H. pylori and COVID-19 was discovered, especially in females.
Conclusion: H. pylori-infected patients are more susceptible to COVID-19 than other persons without H. pylori infections.
Keywords:

References
1. Sun Y, Dong Y, Wang L, Xie H, Li B, Chang C, et al. Characteristics and prognostic factors of disease severity in patients with COVID-19: The Beijing experience. J Autoimmun. 2020;112:102473. [Link] [DOI:10.1016/j.jaut.2020.102473] [PMID] [PMCID]
2. Vetter P, Vu DL, L'Huillier AG, Schibler M, Kaiser L, Jacquerioz F. Clinical features of covid-19. BMJ. 2020;369:m1470. [Link] [DOI:10.1136/bmj.m1470] [PMID]
3. Rodriguez-Morales AJ, Bonilla-Aldana DK, Balbin-Ramon GJ, Rabaan AA, Sah R, Paniz-Mondolfi A, et al. History is repeating itself: Probable zoonotic spillover as the cause of the 2019 novel Coronavirus Epidemic. Infez Med. 2020;28(1):3-5. [Link]
4. Sonkar C, Kashyap D, Varshney N, Baral B, Jha HC. Impact of gastrointestinal symptoms in COVID-19: A molecular approach. SN Compr Clin Med.2020;4:1-12. [Link] [DOI:10.1007/s42399-020-00619-z] [PMID] [PMCID]
5. Al Sulami AA, Al Taee AMR, Juma'a MG. Isolation and identification of Helicobacter pylori from drinking water in Basra governorate, Iraq. East Mediterr Health J. 2020;16(9):920-5. [Link] [DOI:10.26719/2010.16.9.920]
6. Mezmale L, Coelho LG, Bordin D, Leja M. Review: Epidemiology of helicobacter pylori. Helicobacter. 2020;25(51):e12734. [Link] [DOI:10.1111/hel.12734] [PMID]
7. Baj J, Forma A, Sitarz M, Portincasa P, Garruti G, Krasowska D, et al. Helicobacter pylori virulence factors-mechanisms of bacterial pathogenicity in the gastric microenvironment. Cells. 2020;10(1):27. [Link] [DOI:10.3390/cells10010027] [PMID] [PMCID]
8. Balamtekin N, Artuk C, Arslan M, Gülşen M. The effect of helicobacter pylori on the presentation and clinical course of coronavirus disease 2019 infection. J Pediatr Gastroenterol Nutr. 2021;72(4):511-3. [Link] [DOI:10.1097/MPG.0000000000003005] [PMID] [PMCID]
9. Abate BB, Kassie AM, Kassaw MW, Aragie TG, Masresha SA. Sex difference in coronavirus disease (COVID-19): A systematic review and meta-analysis. BMJ Open. 2020;10(10):e040129. [Link] [DOI:10.1136/bmjopen-2020-040129] [PMID] [PMCID]
10. Kushwaha S, Khanna P, Rajagopal V, Kiran T. Biological attributes of age and gender variations in Indian COVID-19 cases: A retrospective data analysis. Clin Epidemiol Glob Health. 2021;11:100788. [Link] [DOI:10.1016/j.cegh.2021.100788] [PMID] [PMCID]
11. Peckham H, De Gruijter NM, Raine C, Radziszewska A, Ciurtin C, Wedderburn LR, et al. Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission. Nat Commun. 2020;11:6317. [Link] [DOI:10.1038/s41467-020-19741-6] [PMID] [PMCID]
12. Pradhan A, Olsson PE. Sex differences in severity and mortality from COVID-19: Are males more vulnerable? Biol Sex Differ. 2020;11(1):53. [Link] [DOI:10.1186/s13293-020-00330-7] [PMID] [PMCID]
13. Klein SL, Flanagan KL. Sex differences in immune responses. Nat Rev Immunol. 2016;16:626-38. [Link] [DOI:10.1038/nri.2016.90] [PMID]
14. Cai KC, Van Mil S, Murray E, Mallet JF, Matar C, Ismail N. Age and sex differences in immune response following LPS treatment in mice. Brain Behav Immun. 2016;58:327-37. [Link] [DOI:10.1016/j.bbi.2016.08.002] [PMID]
15. Naoum FA, Ruiz ALZ, Martin FHDO, Brito THG, Hassem V, Oliveira MGDL. Diagnostic and prognostic utility of WBC counts and cell population data in patients with COVID‐19. Int J Lab Hematol. 2021;43(S1):124-8. [Link] [DOI:10.1111/ijlh.13395] [PMID] [PMCID]
16. Wang X, Fang J, Zhu Y, Chen L, Ding F, Zhou R, et al. Clinical characteristics of non-critically ill patients with novel coronavirus infection (COVID-19) in a Fangcang Hospital. Clin Microbiol Infect. 202;26(8):1063-8. [Link] [DOI:10.1016/j.cmi.2020.03.032] [PMID] [PMCID]
17. Xie H, Zhao J, Lian N, Lin S, Xie Q, Zhuo H. Clinical characteristics of non‐ICU hospitalized patients with coronavirus disease 2019 and liver injury: a retrospective study. Liver Int. 2020;40(6):1321-6. [Link] [DOI:10.1111/liv.14449] [PMID] [PMCID]
18. Tanni F, Akker E, Zaman MM, Figueroa N, Tharian B, Hupart KH. Eosinopenia and COVID-19. J Osteopath Assoc Med. 2020;120(8):504-8. [Link] [DOI:10.7556/jaoa.2020.091] [PMID]
19. Ponti G, Maccaferri M, Ruini C, Tomasi A, Ozben T. Biomarkers associated with COVID-19 disease progression. Crit Rev Clin Lab Sci. 2020;57(6):389-99. [Link] [DOI:10.1080/10408363.2020.1770685] [PMID] [PMCID]
20. Henry BM. COVID-19, ECMO, and lymphopenia: A word of caution. Lancet Respir Med. 2020;8(4):e24. [Link] [DOI:10.1016/S2213-2600(20)30119-3]
21. Zhang M, Feng C, Zhang X, Hu S, Zhang Y, Min M, et al. Susceptibility factors of stomach for SARS-CoV-2 and treatment implication of mucosal protective agent in COVID-19. Front Med (Lausanne). 2021;7:597967. [Link] [DOI:10.3389/fmed.2020.597967] [PMID] [PMCID]
22. Lansbury L, Lim B, Baskaran V, Lim WS. Coinfections in people with COVID-19: A systematic review and meta-analysis. J Infect. 2020;81(2):266-75. [Link] [DOI:10.1016/j.jinf.2020.05.046] [PMID] [PMCID]
23. Rawson TM, Moore LS, Zhu N, Ranganathan N, Skolimowska K, Gilchrist M, et al. Bacterial and fungal coinfection in individuals with coronavirus: A rapid review to support COVID-19 antimicrobial prescribing. Clin Infect Dis. 2020;71(9):2459-68. [Link] [DOI:10.1093/cid/ciaa530] [PMID] [PMCID]
24. Langford BJ, So M, Raybardhan S, Leung V, Westwood D, MacFadden DR, et al. Bacterial coinfection and secondary infection in patients with COVID-19: A living rapid review and meta-analysis. Clin Microbiol Infect. 2020;26(12):1622-9. [Link] [DOI:10.1016/j.cmi.2020.07.016] [PMID] [PMCID]

Add your comments about this article : Your username or Email:
CAPTCHA