en سلامت جانبازان يا معلولان Veterans or Handicapped Health توصیفی و نظرسنجی Descriptive & Survey <span style="font-size:12pt"><span style="line-height:normal"><span new="" roman="" style="font-family:" times=""><span style="color:#0070c0"><b><span style="font-size:10.0pt"><span cambria="" style="font-family:"><span style="color:#f79646">Aims:</span></span></span></b><span style="font-size:10.0pt"><span cambria="" style="font-family:"> </span></span></span><span style="color:#000000;"><span style="font-size:10.0pt"><span cambria="">Although vaccines have been developed for COVID-19, the virus continues to present problems to the health sector. T</span></span></span><span style="color:#0070c0"><span style="font-size:10.0pt"><span cambria="" style="font-family:"><span style="color:black">he current study assessed thyroid function in all hospitalized patients diagnosed with the virus to ascertain whether COVID-19 infection was linked to thyroid function abnormalities.</span></span></span><b><span style="font-size:10.0pt"><span style="font-family:"Cambria",serif"></span></span></b></span></span></span></span><br> <span style="line-height:normal"><b><span style="font-size:10.0pt"><span cambria="" style="font-family:"><span style="color:#f79646">Instrument & Methods:</span></span></span></b><span style="font-size:10.0pt"><span cambria="" style="font-family:"> An observational cohort study was conducted on all COVID-19-positive patients hospitalized in the Al-Fourat Al-Awsat Hospital in Al-Kufa, Iraq, between September 2021 and April 2022. 208 potential patients were tested during this period, and 150 COVID-19 patients and 50 COVID-19-negative individuals were selected. </span></span><span style="font-size:10.0pt"><span cambria="" style="font-family:">A sample of blood was collected during hospitalization. A serum was used to determine the thyroid-stimulating hormone. </span></span></span><br> <span style="line-height:normal"><b><span style="font-size:10.0pt"><span cambria="" style="font-family:"><span style="color:#f79646">Findings:</span></span></span></b> <span style="font-size:10.0pt"><span cambria="" style="font-family:">Hypertension, shortness of breath, diabetes, liver dysfunction, and cardiac and pro-inflammatory diseases were the most frequent comorbidities in COVID-19 patients. The association between COVID-19 and Control groups indicated a significant difference in age, body mass index, gender, systolic- and diastolic blood pressure, fasting blood sugar, HbA1C, alanine aminotransferase, and aspartate aminotransferase. </span></span><span style="font-size:10.0pt"><span cambria="" style="font-family:">Also, the analysis indicated a significant (p<0.001) difference between COVID-19 patients and the control group in the level of TSH. </span></span></span><br> <span style="line-height:normal"><b><span style="font-size:10.0pt"><span cambria="" style="font-family:"><span style="color:#f79646">Conclusion:</span></span></span></b><span style="font-size:10.0pt"><span cambria="" style="font-family:"> Thyroid impairment is frequent in most individuals admitted to the hospital with a COVID-19 infection. Low </span></span><span style="font-size:10.0pt"><span cambria="" style="font-family:">thyroid-stimulating hormone </span></span><span style="font-size:10.0pt"><span cambria="" style="font-family:">level is a reliable indicator of poor prognosis in COVID-19-infected individuals.</span></span></span> Thyroid-Stimulating Hormone,Interlukin-6,Nuclear factor-κB,D-Dimer,COVID-19, 447 452 http://ijwph.ir/browse.php?a_code=A-10-2156-1&slc_lang=en&sid=1 M.A. Al-Barqaawi 15300319475328460027548 15300319475328460027548 Yes Department of Biochemistry, Faculty of Medicine, University of Kufa, Kufa, Iraq Z.T. Al_Joubouri 15300319475328460027549 15300319475328460027549 No Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Kufa, Kufa, Iraq S.L. Ibrahim 15300319475328460027550 15300319475328460027550 No Department of Clinical Laboratory Sciences, Faculty of Pharmacy, University of Kufa, Kufa, Iraq