Iranian Journal of War and Public Health
طب جانباز
Iran J War Public Health
Medical Sciences
http://ijwph.ir
153
ijwph
2008-2622
2008-2630
10.58209/ijwph
en
jalali
1400
6
1
gregorian
2021
9
1
13
4
online
1
fulltext
en
Variation in the Outcome following Intralesional 5-FU in the Treatment of Various Forms of Cutaneous Warts in Iraqi Patients based on Clinical Presentation
آمار و اپیدمیولوژی معلولیتهای ناشی از جنگ/حادثه
Epidemiology and Statistics of War/Accident Related Injuries
پژوهشی اصيل
Original Research
<div style="text-align: justify;"><strong>Aims: </strong>The current study was conducted to see the safety and efficacy of intralesional 5-FU in treating cutaneous warty lesions in a sample of Iraqi patients.<br>
<strong>Methods: </strong>This experimental study was conducted in patients with various warty skin lesions from August 2020 to August 2021. Sixty patients visited the dermatology unit at Aldiwaniyah teaching hospital, Iraq, and were selected for the study. The new solution containing 4mL of 50mg/mL 5-fluorouracil was injected strictly intralesionally till blanching of the lesion occurred. After two weeks of 5-fluorouracil injection, a black ecchymosed eschar developed, which was pared, and residual warts, if present, were injected a second time. The patients were followed up to 3 months and then quarterly up to 1 year. Persistence of wart after three months of the last injection was taken as a failure of treatment. The statistical analysis was done with the SPSS 16 and Excel 2007 using the Chi-square test.<br>
<strong>Findings: </strong>The complete response to treatment was seen in 200 (80.0%), partial response was seen in 37 (14.8%), and no response was recorded in 13 (5.2%) of cases. There was no significant association between size of warty lesion and response to intralesional 5-FU (p=0.154); however, there was a significant association between type of warty lesion and response to intralesional 5-FU (p=0.046).<br>
<strong>Conclusion: </strong>Intralesional 5-FU appears to be highly effective in treating cutaneous warts; however, the response is influenced by the type of skin lesion, being maximal with palmoplantar wart and least common with the skin lesion periungual lesions.</div>
Intralesional 5-FU,Cutaneous Warts,Iraq,
235
238
http://ijwph.ir/browse.php?a_code=A-10-1822-1&slc_lang=en&sid=1
S.A.
Bdaiwi
15300319475328460023885
15300319475328460023885
Yes
Lecturer/ dermatology specialist/ Department of Medicine, College of Medicine, University of Al- Qadisiyah, Iraq
R.H.
Abdul - Saheb
15300319475328460023886
15300319475328460023886
No
Diwaniyah Teaching Hospital, Al-Qadisiyah, Iraq