Introduction: This study aims to examine the effectiveness of Emotional Schema Therapy on The Emotional Schema & Cognitive Emotion Regulation Strategies of patients suffering from Post-Traumatic Stress Disorder (PTSD).

Method: 6 patients from the clients of psychiatric clinic of Baqiyatallah hospital, were selected through available sampling, matched together and then divided into 3 groups (Emotional Schema Therapy combined with Medications, Cognitive Behavioral Therapy combined with Medications & Medications) Patients were examined 5 & 3 times by Leahy Emotional Schema Scale (LESS) and the Short Form of Cognitive Emotion Regulation Questionnaire (CERQ-18) and The Persian versions of the Impact of Event Scale-Revise (IES-R). To analyze the data, indexes of effect size, cohen’s d, process changes, slope and interpretation of ups & downs in charts were employed.

Result:  After treatment, scores of patients who Emotional Schema Therapy received showed decrease in Negative Emotional Schema(Rumination, guilt, uncontrollability) & Maladaptive Cognitive Emotion Regulation strategies (Self-blaming, Rumination, Catastrophizing) additionally, in some Adaptive Cognitive Emotion Regulation strategies (Positive refocusing, Refocusing on planning, Positive Reappraisal)and Adaptive Emotional Schema (higher values, acceptance, consensus, Comprehensibility) an increase was observed.

Conclusion: Emotional Schema Therapy via targeting directly mechanisms of pathological Emotional Schemas & Maladaptive Cognitive Emotion Regulation strategies. can be appropriate choice for treatment of Post-Traumatic Stress Disorder (PTSD).